TY - JOUR AU - Roviello, Giandomenico PY - 2019 TI - To surrogate or not surrogate: an ancient dilemma without a happy ending JF - Journal of Hospital Management and Health Policy; Vol 3 (March 2019): Journal of Hospital Management and Health Policy Y2 - 2019 KW - N2 - Haslam et al . performed an analysis of surrogate validation studies (1), in order to evaluate the strength of correlation between overall survival (OS) and surrogate markers. The analysis included 78 studies that according the inclusion criteria were meta-analyses of randomised controlled trials that investigated the validation as surrogate endpoint for survival of progression free survival or tumour response rate. UR - https://jhmhp.amegroups.org/article/view/4927